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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKACA
All Species:
29.09
Human Site:
S326
Identified Species:
58.18
UniProt:
P17612
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17612
NP_002721.1
351
40590
S326
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
Chimpanzee
Pan troglodytes
XP_001171437
427
49115
S402
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
Rhesus Macaque
Macaca mulatta
O62846
209
24077
F185
G
Y
L
Q
V
T
D
F
G
F
A
K
R
V
K
Dog
Lupus familis
XP_867543
351
40605
S326
F
R
G
S
G
D
T
S
N
F
D
D
Y
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P05132
351
40552
S326
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
Rat
Rattus norvegicus
P27791
351
40601
S326
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422379
398
45968
S373
C
R
G
P
G
D
T
S
N
F
D
D
Y
E
E
Frog
Xenopus laevis
Q6GPN6
434
49096
N399
F
T
E
E
P
V
P
N
S
I
G
Q
S
P
D
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
N398
F
T
D
E
P
V
P
N
S
I
G
C
S
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12370
353
40820
S328
C
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P21137
404
46327
R377
V
D
G
P
A
D
T
R
H
F
V
E
E
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
S353
T
S
G
I
G
D
T
S
L
F
D
Q
Y
P
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
51.2
93.1
N.A.
98
98
N.A.
N.A.
81.4
35.2
34.8
N.A.
82.4
N.A.
68.5
N.A.
Protein Similarity:
100
81.9
56.7
95.4
N.A.
99.4
99.1
N.A.
N.A.
84.6
54.1
53.1
N.A.
90
N.A.
78.4
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
100
100
N.A.
N.A.
86.6
6.6
6.6
N.A.
93.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
N.A.
93.3
26.6
26.6
N.A.
93.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
9
0
0
75
9
0
0
0
67
59
0
0
17
% D
% Glu:
0
0
9
17
0
0
0
0
0
0
0
9
9
59
67
% E
% Phe:
59
0
0
0
0
0
0
9
0
84
0
0
0
0
0
% F
% Gly:
9
0
75
0
67
0
0
0
9
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% I
% Lys:
0
42
0
0
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
59
0
0
0
0
0
0
% N
% Pro:
0
0
0
59
17
0
17
0
0
0
0
0
0
25
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
9
% Q
% Arg:
0
17
0
0
0
0
0
9
0
0
0
0
9
0
0
% R
% Ser:
0
9
0
9
0
0
0
67
17
0
0
0
17
0
0
% S
% Thr:
9
17
0
0
0
9
75
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
17
0
0
0
0
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _